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March 03, 2020 3 min read


Signs and symptoms of magnesium deficiency include, but are not restricted to low stress tolerance and poor sleep. Magnesium helps to maintain equilibrium in the body and the mind, and is thus reduced in deficient states. As a result, key neurotransmitters in the brain begin to alter their response, leading to low stress tolerance and poor sleep. Magnesium supplementation is vital to maintain equilibrium for everyday function.


Magnesium is an essential mineral that our body requires for day-to-day function. As we previously alluded to in our previous blog on ‘Magnesium Deficiency1’, signs and symptoms of deficiency include low stress tolerance and poor sleep. Today’s blog is going to discuss how this manifests and the potential implications it can have for you.

Magnesium & Stress

Stress and anxiety are major buzzwords in society today, particularly with the increasing focus on mental health. When defining stress, we like to keep it as simple and short as possible. A study into stress by Tsigos, Kyrou and Kassi et al (2016)2 defined it as “a state of threatened homeostasis caused by intrinsic or extrinsic adverse forces.” As complicated as that sounds, the paper implies that internal or external forces or stressors can negatively impact our body and mind’s state of equilibrium. Magnesium plays a major role in maintaining this equilibrium state as it is involved in a variety of cellular processes3. In fact, over 325 enzymes (molecules that help speed up chemical reactions in our body) are magnesium dependent, with the majority of these found in our central nervous system.

 How does Stress relate to Magnesium?

In periods of stress, magnesium has been shown to move from within the cell (intracellular) into our blood plasma (extracellular) 3, and later excreted in your urine. This is a protective mechanism by the body to minimise the adverse effects of stress. In magnesium deficient states, the body’s tolerance to stress3is reduced due to the presence of glutamate4. Glutamate is known to act on the NMDA receptors in the brain, which in turn leads to an increase in stress and anxiety4. To summarise, magnesium deficiency will lead to a reduction in the equilibrium in the mind and body, diminishing the body’s tolerance to stress and anxiety.

 Magnesium, stress & sleep

Do you feel stressed when you don’t sleep well? Or do you find your sleep impacted when you are stressed? There’s a good reason for that. With increased glutamate present in the body as a result of magnesium deficiency, it suppresses a neurotransmitter in our brain known as GABA4. GABA is an inhibitory neurotransmitter, which means it lowers the activity of neural cells in the brain and central nervous sytem5. Glutamate and GABA are closely linked. Their relationship can be thought of as two people on a see saw. Too much glutamate will suppress GABA, thus reducing the equilibrium state in the body, and therefore result in increased stress and disturbed sleep.

 Magnesium supplementation is vital to maintain the status quo your body needs to function day-to-day. Our magnesium gel & spray range is highly concentrated and can help reduce the experience of restless and disturbed sleep. No one likes to be stressed, and no one likes to be sleep deprived!

-Aust L # 315181        Magnesium Spray

-Aust L # 315378        Magnesium Gel


  1. https://www.abundantnaturalhealth.com/blogs/news/what-is-magnesium-and-magnesium-deficiency
  2. https://www.ncbi.nlm.nih.gov/books/NBK278995/
  3. https://www.ncbi.nlm.nih.gov/books/NBK507250/
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452159/
  5. https://thesleepdoctor.com/2018/06/19/understanding-gaba/

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